Leafly Strain of the Year 2025 Nominee: Sour Diesel, also known as "Sour D" and "Sour Deez," is a popular hybrid marijuana strain made by crossing Chemdawg and Super Skunk. Sour Diesel effects are dreamy, cerebral, fast-acting and energizing. This strain features a pungent flavor profile that smells like diesel. Medical marijuana patients choose Sour Diesel to help relieve symptoms associated with depression, pain, and stress. Fun fact: Sour Diesel first became popular in the early 1990s and has been legendary ever since.